The disease, also known as follicular mucin disease (follicular mucinosis), its characteristic feat

The disease, also known as follicular mucin disease (follicular mucinosis), its characteristic features for hair removal, follicular papules and erythema slightly elevated limitations. Mucinous alopecia hitherto unknown etiology, bacterial infections, viral infections, autoimmune reactions reported are exactly confirmed. Clinical classification of benign type (skin lesions seasonal affective disorder only) and malignant type (with cancer). The clinical features of benign type is twelve or multiple non-inflammatory scaly patches, or inflammatory erythema, slightly elevated in normal skin, there is a cluster of spots follicular papules, small number of patients seen flat or dome-shaped plaques or nodules, soft, sometimes squeezed out of the hair follicle involvement mucin. Damage at all rash characteristic of hair removal is more common in the head, face, neck, is also found in the trunk and limbs, damage, such as the head, then sometimes seasonal affective disorder patchy hair loss significantly (note with alopecia areata differentiated); hair follicles can suffer damage, resulting in permanent hair loss, but also has not been destroyed, after more hair regrowth. This type occurs mainly in children and youth. This type of need and alopecia, alopecia areata false, sarcoidosis, lymphocytic infiltration of the skin, fungal skin infections, ring granulomas, small spines moss, hair red rosea, seasonal affective disorder seborrheic dermatitis. Malignant form occurs in patients over the age of 40, in addition seasonal affective disorder to the type of benign lesions, but also accompanied lymphoreticular tissue tumors, such as the reticular cell hyperplasia, Dong-like granuloma, lymphoma disease, clinical appeared most invasive plaque diffuse distribution, the patient died of lymphoreticular tissue tumors or other complications. Although this type of hair loss has infiltrative plaques and features needed with simple bacteria-like granulomas seasonal affective disorder occurring, sarcoidosis, seasonal affective disorder phase identification plaque psoriasis deputy. Histopathological features, at the beginning of the sebaceous glands and hair follicles of the outer root sheath of cystic seasonal affective disorder epithelial cells form a gap (due to the reticular degeneration), followed by deposition of mucin in its inside. This sticky protein is acidic mucopolysaccharide by Giemsa staining and Alcian blue staining has metachromatic composition. Mucin PAS stain was negative. Skin inflammatory cell infiltration, lymphocytes, eosinophilic leukocytes, tissue-based, inflammatory infiltration around the hair follicles to be more pronounced. Malignant type of pathology as lymphoreticular tissue tumors has changed. The disease lesions within the affected hair follicles inside and outside the organization and found a large number of IgA and IgG antibody deposition.